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The Serie A season for 2025/26 starts with Matchweek 1 on Saturday, August 23. It kicks off with Genoa playing against Lecce and Sassuolo going up against Napoli to start the weekend.

Later on Saturday, the action moves to San Siro for the match between Milan and Cremonese, and there’s also a big game in the capital where Roma will take on Bologna. On Sunday, Cagliari will play against Fiorentina, Como will celebrate their return to the top league by facing Lazio, and there are exciting matches like Atalanta vs Pisa and Juventus starting their season against Parma.

The first round will finish on Monday with Udinese playing against Verona, and then Inter will begin their season at home against Torino. Matchweek 1 is expected to give us a sneak peek at the teams that might compete for the title, those hoping for European spots, and the new teams that are eager to show what they can do.

Serie A Fixtures Matchweek 1

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Genoa vs Lecce

Genoa kicks off the season at the Stadio Luigi Ferraris against Lecce.

Last season, Genoa finished in 13th place, partly due to a midseason coaching change to Patrick Vieira, who helped them perform well at home. They recently displayed good form by winning their first competitive match of the season 3:0 in the Coppa Italia.

Lecce, who managed to avoid relegation last year, have strengthened their squad but are facing a challenging away game with some defensive issues still present. Manager Eusebio Di Francesco is back for a second term this summer.

Genoa comes into this match unbeaten in their last nine home games against Lecce, having won the last three matches with the same score of 2:1.

DC 1X (Genoa to Win or Draw)

Predicted CS: 2:1

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Sassuolo vs Napoli

Sassuolo, who just got promoted, will play against Napoli, the favorites for the title, at the Mapei Stadium.

After a great run in Serie B, Sassuolo is back in Serie A and will focus on a strong defense. Their deep pressing strategy will really be tested against Napoli’s fast midfield and creative attackers.

Napoli, coached by Antonio Conte and seen as the reigning champions with a strong team, are expected to take control early in the game. They have stars like Romelu Lukaku, who is aiming to be the top scorer. Napoli also brought in Kevin De Bruyne, Scott McTominay, and Sam Beukema to make their midfield and defense even better.

While Napoli wants to show they are the best, Sassuolo hopes to surprise everyone and set a strong defensive standard right from the start.

2 (Napoli to Win)

Predicted CS: 0:2

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Milan vs Cremonese

AC Milan kicks off their season at San Siro against the newly promoted team, Cremonese, looking for a strong beginning to compete for the Scudetto.

Milan have brought back Massimiliano Allegri as their head coach, hoping to bring the club back to its former glory after a tough last season. Some of the key new players include midfielders Luka Modric, Samuele Ricci, Ardon Jashari, Pervis Estupinan, Koni De Winter, and Zachary Athekame.

Cremonese is back in Serie A but doesn’t have much experience in the top league. They got promoted through the Serie B playoffs, but they have a record of struggling in season openers, having lost their last eight matches at the start of the season.

AC Milan is expected to take charge of the midfield and control the game’s tempo, taking advantage of Cremonese’s past weaknesses.

1 & T1 2+ (Milan to Win & Milan Over 1.5)

Predicted CS: 3:0

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Roma vs Bologna

Roma will face Bologna at the Stadio Olimpico in an exciting match between two teams hoping to make it to Europe.

Roma has appointed Gian Piero Gasperini as their new head coach. Gasperini comes from Atalanta, where he had a great nine-year run. His hiring shows that Roma wants to compete for Champions League spots after just missing out last season.

Bologna had a strong performance in 24-25 and might be tough to beat with their game plan. They finished their last season on a high note by winning the Coppa Italia, which is their first big trophy since 1974. They ended up 9th in Serie A but got into the Champions League because of their cup win.

This match could be very close, with both teams aiming for top-six finishes.

GG (BTTS-Yes)

Predicted CS: 1:1

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Cagliari vs Fiorentina

Cagliari is set to host Fiorentina at the Unipol Domus, where the home team’s strong record will be put to the test.

Last season, Cagliari successfully stayed out of the relegation zone, finishing in 14th place under coach Davide Nicola, who is still leading the team. Cagliari counts on their strong home performance, often making it tough for visiting teams with their solid defense and familiarity with the home ground.

Even though Raffaele Palladino got a contract extension, he and the club agreed to part ways in May 2025. His replacement, Stefano Pioli, has come back to the club on a three-year contract, bringing valuable experience and stability to Fiorentina.

We anticipate a close match. Cagliari’s reliable home play and teamwork will face off against Fiorentina’s strategic changes.

X2 (Fiorentina to Win or Draw)

Predicted CS: 1:2

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Como vs Lazio

Como faces Lazio at the Stadio Giuseppe Sinigaglia in a tough opening match.

Como, who just got promoted and is coached by Cesc Fabregas, finished 10th in their first season back, which is a great accomplishment for a team returning to Serie A after 21 years. They set a club record with six straight wins, showing their competitive spirit and ability to attack.

Lazio ended the 24–25 season in 7th place, earning 65 points, and just missing out on the Europa League spots. They had a strong away record with 11 wins, 1 draw, and 6 losses when playing on the road.

Como’s home advantage and energetic team might create some early opportunities, but Lazio’s better organization, control in midfield, and reliability on the road should help them take charge.

GG (BTTS-Yes)

Predicted CS: 1:2

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Atalanta vs Pisa

Atalanta is set to play against the newly promoted team, Pisa, at the Gewiss Stadium.

Atalanta, known for their aggressive high-pressing game led by Gian Piero Gasperini, usually puts a lot of pressure on new teams. They finished 3rd in Serie A last season, which included impressive runs in both the Champions League and the Super Cup.

Pisa is back in Serie A after being away for 34 years, and they are coached by Alberto Gilardino, who focuses on strong defense and staying compact.

While Atalanta is the stronger team, Pisa’s strategy for away games and their current form could make them a tough opponent.

1 & T1 2+ (Atalanta to Win & Over1.5)

Predicted CS: 3:0

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Juventus vs Parma

Juventus faces promoted Parma at the Allianz Stadium, with the Old Lady seen as a strong contender for the title along with Napoli and Inter.

Igor Tudor starts his first full season as the head coach after leading Juventus to a Champions League spot last season. The team has added Jonathan David, Joao Mario, and Francisco Conceicao to strengthen the squad. They have remained undefeated in four friendly matches, including wins against Borussia Dortmund and Atalanta.

Carlos Cuesta steps in after working as Mikel Arteta’s assistant at Arsenal. Parma is back in Serie A after being away for three years. They are likely to play defensively, aiming to stay in the top division.

Juventus is expected to control the game and take charge early on. Parma’s defensive strategy might limit their chances to score.

1 (Juventus to Win)

Predicted CS: 2:0

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Udinese vs Verona

Udinese host Hellas Verona at the Bluenergy Stadium in a matchup of two sides expected to battle in the lower mid-table.

Udinese, under Kosta Runjaic, enters his second season after guiding Udinese to a comfortable 12th-place finish in Serie A last term. Udinese have strengthened their defense with new signings, aiming to improve upon their previous season’s performance.

Verona manager Paolo Zanetti continues his tenure, focusing on maintaining Hellas Verona’s Serie A status. Last Season Verona finished 14th in Serie A. On the road, Verona struggled, earning only 20 points from 19 matches

This encounter often ends in tight results, with Udinese holding the historical edge.

0-2 (Under 2.5)

Predicted CS: 1:0

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Inter vs Torino

Inter wraps up the matchday at San Siro against Torino, looking to show they are serious about winning the title early on.

Cristian Chivu starts his job as Inter Milan’s head coach, taking over from Simone Inzaghi. Chivu takes charge of a team full of talent, including Yann Sommer, Marcus Thuram, Lautaro Martinez, and maybe new player Ademola Lookman from Atalanta.

Torino is still led by Ivan Juric, who is known for his strict and organized style. Even though Torino has a solid team, they don’t have the star players to match top teams like Inter. They will focus on being strong defensively and taking advantage of counter-attacks.

Inter’s strong home performance and better quality should help them win easily and start their season off right.

1 & T1 2+ (Inter to Win & Over 1.5)

Predicted CS: 2:0

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Kindly be advised that all odds are accurate as of the publication date and time indicated, and they may be subject to alterations.

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