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Matchweek 6 of the 2025/26 Premier League season is set to bring more excitement and important matchups across the standings. The action kicks off on Saturday, September 27, with Brentford taking on Manchester United in the early game. United aims to maintain their push for a top-four finish, while Brentford hopes their home fans can help them pull off a surprising win. This fixture is part of the wider Premier League predictions for the current matchweek, where each game is reviewed in the context of form and scheduling.

At 16:00, four matches will happen at the same time. Chelsea will face Brighton at Stamford Bridge in what should be a battle of different playing styles, while Crystal Palace will host Liverpool in a challenging match for the Reds at Selhurst Park. Leeds will go up against Bournemouth in a fight for teams trying to avoid the lower half of the table, and reigning champions Manchester City are expected to win at the Etihad against Burnley.

Later that evening, Nottingham Forest will play Sunderland at 18:30, followed by Tottenham taking on Wolves in the late game at 21:00. Spurs will aim to show they can be consistent, but Wolves are always a tough team to beat, especially when playing away.

On Sunday, Aston Villa will play Fulham at Villa Park, and then all attention will turn to St James’ Park where Newcastle will clash with Arsenal in one of the most exciting matches of the weekend. Both teams are looking to secure a spot in the Champions League, and this game could be a crucial early challenge.

The round wraps up on Monday night with Everton facing West Ham at Goodison Park, a match that promises to be intense as both teams battle for important points in the mid-table.

Premier League Predictions Matchweek 6

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Brentford vs Manchester Utd

Brentford started the season in poor form. Last round, they lost away to Fulham with a score of 3–1, marking their third defeat in the last five matches. The “Bees” have only one win and one draw, with a total of 6 goals scored and 10 conceded.

Young attackers like Dango Ouattara and Igor Thiago are trying to bring some freshness to the attack. The team is led by Keith Andrews, who is working to establish balance in their play and boost the players’ confidence.

Manchester Utd achieved a significant victory against Chelsea, winning 2–1 last weekend, which lifted their confidence after a mixed start to the season. Ruben Amorim’s team has 2 wins, 1 draw, and 2 losses in their last five matches. Fernandes and Casemiro were the heroes who scored against the “Blues” This season, after five matches played, they have scored 6 goals and conceded 8.

Manchester Utd has more individual quality, and it’s about time they string together a series of positive results, but Brentford will be motivated to earn points at home. Given the form both teams are in, we give the edge for victory to the visitors.

2 (Manchester Utd to Win)

Predicted CS: 1:2

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Chelsea vs Brighton

Last weekend, Chelsea lost the big derby against Manchester United 2–1, leaving them with 8 points in 6th place. Their form is inconsistent, even though the team has the potential to reach the top. Palmer is a key threat in attack, but he is dealing with injury issues. So far, Enzo Fernandez and Caicedo have stood out.

They have great individual players, and coach Enzo Maresca is still trying to bring harmony to their play. In the Champions League group stage, they were defeated by Bayern Munich away with a score of 3:1, and next week they will visit Benfica.

Brighton played an exciting draw with Tottenham in the previous round, ending the match 2–2. This gave them a point, but their winless streak continues. They have only one win this season, along with two draws and two losses, putting them at 14th place with 5 points. The ‘Seagulls‘ are in the lower part of the table and will try to improve with the help of creative players like Mitoma, Gruda, and the young winger Minteh.

The hosts have better efficiency and quality, while Brighton seems unstable in defense. We expect the home team to secure three points.

1 (Chelsea to Win)

Predicted CS: 0:0

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Crystal Palace vs Liverpool

Crystal Palace is a real surprise. In the last round, they defeated West Ham in London with a score of 1–2 and remained unbeaten in their first five matches. With only two goals conceded, Oliver Glasner’s team is considered to have the strongest defense in the league. Mateta and Esse are the key players for creativity up front. After five matches this season, they have achieved two wins and three draws, placing them in 5th position with 9 points.

Liverpool remains perfect, winning 2–1 against Everton on Saturday and keeping their top position with a maximum of 15 points. Salah, Ekitike, and the new signing Chiesa regularly score goals, while the midfield with Szoboszlai and Mac Allister looks balanced.

They have six consecutive victories, including a Champions League match against Atl. Madrid, which they won 3:2. Next week, they will visit Galatasaray, and some rotations in the team are possible.

Crystal Palace is in stable form, but Liverpool’s championship form is hard to stop. We expect the home team to have a shining moment in the match, so we anticipate at least one goal from both sides.

GG (BTTS-Yes)

Predicted CS: 1:2

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Leeds vs Bournemouth

Leeds showed their character with a guest victory over Wolves, winning 1–3 in the last round. With this win, they reached 7 points and got back into a positive rhythm. Calvert-Lewin, Stach, and Okafor were the goal scorers again. After playing 5 matches, they have two wins, two losses, and one draw, scoring 4 goals and conceding 7.

Bournemouth drew 0–0 with Newcastle and remains among the best with 10 points. The attack featuring Kluivert, Evanilson, and Semenyo is a threat, while their compact midfield keeps them at the top of the table. They are playing excellently under the guidance of Andoni Iraola, and after losing in the first round, they followed up with 3 consecutive wins. They have scored 6 goals and conceded 5.

Leeds plays offensively and will create chances at home, but Bournemouth is strong enough to earn a point. We expect an efficient match with at least 3 goals.

3+ (Over 2.5)

Predicted CS: 2:2

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Manchester City vs Burnley

Manchester City managed to earn a valuable point away at Arsenal with a score of 1–1. They almost secured all 3 points but managed to stop their losing streak. However, with only 7 points and just two wins, the “Citizens” need to find some consistency. Haaland is already the top scorer with 6 goals, while Foden and Reijnders are adding creativity to the team. In the first round of the League phase in the UCL, they defeated Napoli, and next week they will visit Monaco.

Burnley played to a 1–1 draw against Nottingham and remains with just 4 points in 16th place. Scott Parker’s team is struggling with scoring and defense. A big hope lies with Jaidon Anthony, who has scored three goals so far. After 5 matches, they have one win, three losses, and one draw, having scored 5 goals and conceded 8.

Given the quality and tradition of the home team, we expect them to achieve an easy victory and score at least two goals during the match.

1 & T1 2+ (City to Win & City Over1.5)

Predicted CS: 3:0

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Nottingham vs Sunderland

Nottingham played a 1–1 draw against Burnley last week and is currently sitting at 15th place with 5 points. The team often struggles in attack, with Chris Wood being the only one performing well. Ange Postecoglou faces a tough challenge in finding a way to improve the team’s form. After winning in the first round, they have since suffered two losses and two draws. In these 5 matches, they have scored five goals but conceded 9.

Last week, in the group stage of the Europa League, they drew 2:2 against Betis, and next week they will host Midtjylland.

Sunderland has been impressive as a newly promoted team, drawing 1–1 against Aston Villa in the last round, and they are now on a three-match unbeaten streak. They are in 7th place with 8 points, boasting a strong defense and good teamwork. Regis Le Bris can be pleased with how the team started the season, but he knows they can achieve even more. So far, they have scored 6 goals and conceded 4, with Wilson Isidor being particularly effective in attack, having scored 3 goals.

Nottingham will aim to secure all 3 points with the support of their home crowd, but Sunderland has shown they can be a tough opponent. We expect a closely contested match.

X (Draw)

Predicted CS: 1:1

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Tottenham vs Wolves

Tottenham played a 2–2 draw away against Brighton, and after 5 matches this season, they have one loss, one draw, and three wins, placing them in 3rd place with 10 points, which puts them in the top 3. Under the guidance of their new coach Thomas Frank, they look stable. Richarlison and Johnson are key for creating chances and scoring goals.

In the Champions League group stage, they won against Villarreal at home with a score of 1:0, and next week they will visit Bodo/Glimt.

Wolves continued their poor streak and were completely outplayed by Leeds, losing 1:3 at home, marking their fifth consecutive loss. They are still without any points and sit at the bottom of the table, with only 3 goals scored and 12 conceded. Vitor Pereira needs to quickly fix the team’s issues, or they will definitely face relegation from the league this season.

Tottenham is in much better form and is a clear favorite in front of their home crowd. Given Wolves’ defensive mistakes, we expect the home team to win and score at least two goals during the match.

1 & T1 2+ (Tottenham to Win & Tottenham Over1.5)

Predicted CS: 2:0

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Aston Villa vs Fulham

Aston Villa managed to get a draw against Sunderland, ending 1–1, but they still haven’t won in five matches. The team has only scored one goal, even though their defense is holding up well. Ollie Watkins is still the main hope in attack. The team has individual talents, and Unai Emery will need to make serious improvements to get the team back to winning ways.

Тхис week, in the group stage of the Europa League, they faced Bologna and managed to earn three points by winning 1:0, but next week they will visit the tough Feyenoord.

Fulham defeated Brentford 3–1 in a London derby and now has 8 points, with two consecutive wins. Alex Iwobi and Wilson stood out in the attack. They are currently in 8th place with 8 points, and in these 5 matches, they have scored 6 goals while conceding 5. The team is led by Marco Silva, who can be pleased with their early season form.

After a series of disappointments, the hosts need to find their first win, but Fulham could be a tricky opponent. Aston Villa has beaten Fulham in each of their last 6 encounters, but considering the form of both teams, we can expect at least one goal from each side.

GG (BTTS-Yes)

Predicted CS: 1:2

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Newcastle vs Arsenal

Newcastle played to a goalless draw against Bournemouth in their last match, marking their third draw in the last five games. They also have one win and one loss, but their main issue is scoring, with only three goals so far. However, their defense is strong, having conceded just three goals. They are currently in 13th place with six points, and Eddie Howe needs to find a way to get the team back to winning ways.

In the Champions League group stage, they lost their first match away to Barcelona 1-2, and next week they will face Royale Union SG.

Arsenal drew with Manchester City 1-1, keeping them in the title race. The real hero of the match was Martinelli, who scored a goal in the 93rd minute to secure a point. They have ten points and look solid defensively, having only conceded two goals this season, while scoring ten. Gyokeres, Martinelli, and Saka are rising stars and bring freshness to the attack.

In the Champions League group stage, they defeated Ath Bilbao away 0-2, and next week they will host Olympiacos Piraeus.

Newcastle is a tough opponent, especially at home, and Arsenal has big ambitions this season, aiming for all three points.

2 (Arsenal to Win)

Predicted CS: 1:2

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Everton vs West Ham

Everton played a derby against Liverpool and lost narrowly 2–1, even though they showed brave play. With 7 points, the team looks better than last year and has a stable formation with Grealish as the most creative player. In attack, they have the excellent Ndiaye and Beto. After 5 matches, they have achieved two wins, one draw, and two losses, scoring 6 goals and conceding 5.

West Ham lost at home last round to Crystal Palace with a score of 1–2, marking their fourth loss this season after five matches. With only 3 points earned from defeating Nottingham, they sit in 19th place and are under great pressure to improve their form. The team is led by Graham Potter, who is struggling to find a solution for a team with quality individuals, but at times they seem disorganized on the field.

Everton has shown much more this season, playing more disciplined, and with the help of their home crowd, we expect them to secure three points.

1 (Everton to Win)

Predicted CS: 2:0

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Looking ahead, upcoming fixtures will be covered in Premier League Matchweek 7 predictions as the season continues.

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